توصيف مقرر المستوى السادس

e.g. 6th  level

There of lecture hours: 2 hrs

There of practical hours: 1 hr

There of self-study hours: 2 hrs

English

By the end of this course students will be able to:

• List biochemistry definitions and topics classifications.

• Describe some disorders of clinical cases.

• Memorize disease states and different laboratory tests and their applications.

• Describe different laboratory tests and their applications.

• Prepare short reports about some clinical cases.

• Collect general information about some medical biochemistry disorders with related topics.

• Summarize clinical findings and extract important data.

• Evaluate given data from understanding medical biochemistry basis.

• Apply the gained knowledge and experience of related topic.

• Work in a group and learn time management.

• Demonstrate some cases in a short report in a written form and orally using appropriate scientific language.

• Choose appropriate data for specific cases, communication with patients.

• Utilize computer technology.

• Manage laboratory training process, analytical laboratory tests.

Content of the Module:

This course presents introductory biochemistry relevant to human health and disease that forms part of the foundation of modern medical practice. The molecular correlation with disease is emphasized throughout the course.

The topics included are:

- Enzymes: introduction, nomenclature, classification, mechanism of action, inhibition and factors affecting activity.

- Vitamins, introduction, nomenclature, classification, mechanism of action, diseases states associated with defeciency.

- Carbohydrates metabolism and disease states associated with disorders of metabolism.

- Lipid metabolis and disease states associated with disorders of metabolism.

- Protein and amino acid metabolism and disease states associated with disorders of metabolism.

- Nucleic acid metabolism and disease states associated with disorders of metabolism.

Examination:

e.g. written examination, presentation

written exams ( 1st midterm exam – 2nd midterm exam – practical exam – final exam) – homeworks and assignments ( theoretical – practical) – Oral presentation – Lab. Reports.
 

e.g. 6th  level /2nd semester

There of lecture hours: 1 hr

There of practical hours: 2 hrs

There of self-study hours: 2 hrs

English

By the end of this course students will be able to:

• Recognize the Theoretical knowledge about microscopy (light microscopy [LM], as well as TEM and SEM).

• Describe the applications of LM, TEM, and SEM, Illumination sources (photons vs. accelerated electrons), Lens systems (glass vs. electro-magnetic), Magnification vs. resolution, Specimen-electron beam interactions.

• Compare between Electron microscope (EM) and Light microscope (LM).

• Explain the Principles and construction of TEM & SEM.

• Summarize and differentiate between specimen preparations for TEM & SEM.

• Work effectively in team.

• Perform the steps required for specimen preparation for transmission electron microscopy (TEM): Fixation and dehydration, Embedding, Ultrathin sectioning (ultramicrotomy), Staining grids with heavy metal stains.

Content of the Module:

• Introduction to electron microscopy : fundamental concepts in electron microscopy; history and pioneers in electron microscopes, the main two types of electron microscopes.

• Light microscopy vs electron microscopy.

• Comparison between Electron microscope (EM) and Light microscope (LM) :Similarities (Arrangement and function of component are similar), Differences between light and electron microscopes.

• The Scale of things and resolving power line.

• Advantages and disadvantages of EM.

• Electrons/wave length/ resolution.

• Relationship between wavelength and resolution: Relationship between wavelength of electron and resolution ,Relationship between electron wavelength and accelerating voltage(de Broglie equation) and Intermediate and high voltage EM (ADVANTEGES AND EXAMPLES).

• Magnification vs. resolution.

• Optics vs electromagnetic lenses, and defect of lenses(lens aberrations).

• Interactions between specimen and electron beam.

• Principles and construction of transmission electron microscope (TEM).

• Specimen preparation for transmission electron microscopy (TEM): Fixation and dehydration, Embedding, Ultramicrotomy (sectioning by ultra-microtome).

• Staining methods : staining of ultra-thin sections by heavy metals stains and contrast and image formation for TEM, Negative staining.

• Principles and applications of scanning electron microscope (SEM).

• Specimen preparation for scanning electron microscopy (SEM):

Fixation, dehydration, Critical point drying, Mounting specimens on stubs
and Sputter coating.

Examination:

e.g. written examination, presentation

written exams ( 1st midterm exam – 2nd midterm exam – practical exam – final exam) – homeworks and assignments ( theoretical – practical) – Oral presentation – Lab. Reports.